#drugdevelopment is an active hashtag on Bluesky. In the last 30 days, 15 people shared 57 posts with it — around 2 a day. Activity is up 0% versus the previous week, peaking on Jul 30 with 5 posts.
Tags most often used together with #drugdevelopment.
media.tenor.com
a man is looking at his cell phone with a follow button in the background .
ALT: a man is looking at his cell phone with a follow button in the background .
www.cell.com
EGFR-directed antibodies promote HER2 ADC internalization and efficacy
Gupta et al. demonstrate that high EGFR expression mediates resistance to HER2 antibody drug conjugates (ADCs) including trastuzumab deruxtecan (T-DXd) by limiting HER2/ADC internalization. The additi...
jamanetwork.com
The Microbiome and Cancer: A Review
This review in the Translational Science series summarizes current evidence regarding the human microbiome and cancer, including how the microbiota in the gut and other anatomical locations affect can...
www.nature.com
‘Publish or perish’ culture blamed for reproducibility crisis
Survey of more than 1,600 biomedical researchers also flagged small sample sizes and cherry-picking of data as leading causes of reproducibility problems.
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social
Wow—one of the most impressive bench-to-bedside stories you’re ever going to see out today @Nature Spatial proteomics of potentially fatal toxic epidermal necrolysis/Stevens-Johnson Syndrome drug reactions identifies JAK/STAT pathway inhibition as effective therapy! www.nature.com/articles/s41...
jamanetwork.com
Heterogeneity of Residual Disease After Neoadjuvant Systemic Therapy in Breast Cancer
This review analyzes the heterogeneity of residual disease after neoadjuvant systemic therapy in patients with breast cancer.
post.citiprogram.org
FDA's New Master Protocol Guidance: Drug Development
As precision medicine expands and development programs become increasingly complex, master protocols may play a growing role in helping sponsors study therapies.
citizenportal.ai
Presenter urges applicants to submit control correspondence for MDD confirmation
The presenter recommended that generic applicants seeking confirmation of an MDD submit a control (controlled) correspondence for regulatory assessment, particularly for products with complex dosing or routes like topicals and ophthalmics.
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