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Bluesky · Hashtag

#cardiovascular

posts · 30d

users

posts / day

1.6

posts / user

-12% vs last week

#cardiovascular is an active hashtag on Bluesky. In the last 30 days, 56 people shared 88 posts with it — around 3 a day. Activity is down 12% versus the previous week, peaking on Sep 14 with 9 posts.

#cardiovascular posts per day (last 30 days)

Related tags

Tags most often used together with #cardiovascular.

#health 10 #heart 9 #cholesterol 7 #stroke 7 #MedSky 6 #CardioSky 5 #diabetes 5 #vaccine 5 #pharmacy 5 #OpenAccess 5 #shingles 5 #Cardiology 5

Posts with #cardiovascular

NORML

@norml.org

about 1 year ago

💚 Older adults who consume #cannabis are no more likely to suffer from adverse #cardiovascular events, such as #heartattack and #stroke, as compared to non-users, according to longitudinal data published in the journal Circulation. #NORML #marijuana

norml.org

Cannabis Not Associated With Elevated Risk of Cardiovascular Events

No more likely to suffer heart attack or stroke compared to non-users

4 13 52

Johannes W. Dietrich

@drjwdietrich.bsky.social

over 1 year ago

#Thyroid hormones profoundly impact the #cardiovascular system. They act at all levels, ranging from the tier of ion currents over cellular processes to the macroscopic levels of myocardial tissue and even the whole organism. 🧪 🩺 #MedSky doi.org/10.3389/fcvm... pubmed.ncbi.nlm.nih.gov/3…

Thyroid hormone signalling involves four different mechanisms. T4 is a prohormone with respect to genomic signaling, but a true fast-acting hormone regarding type 4 action (which is inhibited by the iodothyroacetate TETRAC). Genomic action (type 1, type 2 and mitochondrial signaling) occurs on a slow time scale, whereas non-genomic effects (type 3 and type 4 signaling) represent a fast response (A). Thyroid hormone receptors (THR) usually act as heterodimers. Without thyroid hormone bound they block the transcription together with corepressors. Iodothyronines displace the corepressors and stimulate gene expression together with coactivators (B). Tissue specific distributions of THRs further contribute to the diversity of signaling patterns in the organism (C). AF-1, activation function 1; AF-2, activation function 2; D2, type 2 deiodinase; DBD, DNA-binding domain; HAT, histone acetyl-transferase; HDAc, histone deacetylase; LBD, ligand-binding domain; RXR, retinoid X receptor; TRE, thyroid-hormone response element.

Thyroid hormones have a profound effect on the intracellular processes of rhythm generation. The figure shows mechanisms of rhythm generation in cardiomyocytes based on a model by Maltsev et al. Two loops, an external membrane loop and an internal calcium loop, independently ensure the generation of impulses. Therefore, they provide some redundancy, but they are also intertwined at the stage of slow L-type Ca2+ current (ICaL) activation. Thyroid hormone signalling can modulate both loops simultaneously via interfaces at several sites, and direct myocardial effects of TSH are largely opposing. gK, ionic conductance for K+; INCX, Na+/Ca2+ exchange current; ICaT, T-type Ca2+ current; If , hyperpolarisation-activated “funny” current; IK, voltage-gated K+ current; Ist , sustained non-selective current; Ito, transient outward potassium current; LCR, local Ca2+ release; SERCA, sarcoendoplasmic reticulum Ca2+-ATPase; SR, sarcoplasmic reticulum.

Selected mechanisms of arrhythmogenesis by thyroid hormones at the cellular level. T3 (and other active thyroid hormones) upregulate the gene expression of beta1 and beta2 adrenoceptors via classical genomic signaling, but downregulate protective beta3 adrenoceptor expression. The transcription of critical genes for the formation of gap junctions is downregulated as well. Potassium channels are regulated via classical type 1 signaling and via non-genomic effects (type 4 action) as well. Purple arrows indicate the effects of gene expression (transcription, translation and associated processing steps), green arrows visualize the impact of T3-agonistic thyroid hormones.

$On a macroscopic level, elevated concentrations of thyroid hormones promote arrhythmia by slowing down electrical conduction and reducing the effective refractory period. (A,B) Simplified model of the effects of thyroid hormone signalling facilitating disorders of impulse conduction. Iodothyronine action reduces both the effective refractory period (ERP) and the conduction velocity (θ). As a consequence, the wavelength of excitation λ = ERP x θ may get shorter than the dimensions of a potential re-entry circuit, thus giving rise to re-entrant tachycardia.$

4 8 40

Prof Claire Hills

@chillslincoln79.bsky.social

almost 2 years ago

Want to know more about the 'Expanding applications of therapies based on #GLP1' Check out this latest review by Daniel Drucker 🧪🔬🥼 @natureportfolio.bsky.social 👇👇 #CardiacSky #NephSky #Diabetes #obesity #cardiovascular #kidneydisease #LiverDisease www.nature.com/articles/s41...

www.nature.com

Expanding applications of therapies based on GLP1 - Nature Reviews Endocrinology

The evidence base in support of the use of medicines based on glucagon-like peptide 1 beyond glucose control and weight loss was substantially bolstered in 2024, as clinical trial data report benefits...

2 12 36

Dr. Todd Ewing PhD.

@ewingt-phd.bsky.social

9 months ago

Morning #coffee associated with better #circadian rhythm and #cardiovascular health! www.prevention.com/health…. — 16% less likely to die of any cause — 31% less likely to die of cardiovascular disease — however, no reduction in risk for all-day coffee drinkers! #HappyNewYear #science 🧪

www.prevention.com

This Is the Best Time of Day to Drink Coffee, According to Scientists

Discover why timing your java right matters.

4 13 33

Prof Claire Hills

@chillslincoln79.bsky.social

almost 2 years ago

Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials 🔭🧑‍🔬🥼 #Diabetes #NephSky #CardioSky #Cardiovascular #Cardiovasculardisease #KidneyDisease #Type2Diabetes 👇👇 www.thelancet.com/journal….

www.thelancet.com

Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials

We found evidence that GLP-1 receptor agonists significantly reduce clinically important kidney events, kidney failure, and cardiovascular events.

0 5 29

Christophe Veltsos

@drinfosec.bsky.social

about 1 year ago

🎯🧵 by Dr. @harryspoelstra.bsky.social on the "Cardiovascular Manifestations of Patients with Long COVID" 🚨🚨"1. Everyone with, even the mildest, post-COVID-19( LC) symptoms should get a cardiovascular check-up!" 🚨🚨 Full🧵here: threadreaderapp.com/threa…. #Covid #LongCovid #Cardiovascular

Cardiovascular Manifestations of Patients with Long COVID

🔥More than 50% of LC patients with ‘symptoms’ have Heart damage, according to this interesting Serbian study!

➡️‘This study involved 176 consecutive outpatients in follow-up care (average age 55.9 years; 58.5% male) who experienced symptoms for over 12 weeks (average 6.2 ± 2.7 months), following coronavirus infection (COVID-19).’

➡️‘Long COVID is an unpredictable condition that presents a range of symptoms affecting multiple organ systems.’

➡️‼️‘The dominant cardiovascular symptoms include shortness of breath, effort intolerance or fatigue, palpitations, irregular pulse or premature ventricular beats (PVBs), and chest tightness.’

➡️‘Most patients with long-COVID showed structural and functional changes in their cardiovascular systems, primarily caused by prolonged inflammation.’

➡️‘In our study, patients who presented with high suggestion of long COVID after abnormal clinical and echocardiographic examination had 58.2% abnormal CMR findings.’

➡️‘Pathological cardiac magnetic resonance (CMR) findings were seen in 58.2% of the group of patients with long COVID and cardiovascular manifestation; 43.3% exhibited positive late gadolinium enhancement (LGE), 21.0% had elevated native T1 mapping, and 22.4% had elevated native T2 mapping.’

➡️‘Using multimodality imaging, such as echocardiography and cardiac magnetic resonance (CMR), especially, is crucial.’

➡️‘This multimodality imaging technique is essential to find the mechanisms of predicting chronic myocarditis, early-stage heart failure, and pre-ischemic states, which can lead to serious complications.’

➡️‘Recognizing the specific cardiovascular phenotypes associated with long COVID is essential to provide timely and appropriate treatment.’

Sorry, I’ll say it again:
1. Everyone with, even the mildest, post-COVID-19( LC) symptoms should get a cardiovascular check-up!
2. A GP check-up with ECG is already a good start!
3. Heart LC can be a silent killer!
…

2 13 28

Prof Claire Hills

@chillslincoln79.bsky.social

almost 2 years ago

How the weight loss drug tirzepatide is also helping heart failure patients 👩‍🔬🧪🥼 #CardioSky #NephSky #Obesity #Diabetes #GLP-1 ##heartfailure #cardiovascular 👇👇👇 www.sciencenews.org/artic….

www.sciencenews.org

How the weight loss drug tirzepatide is also helping heart failure patients

Data continue to show that tirzepatide, called Mounjaro for type 2 diabetes and Zepbound for weight loss, is safe and effective, but side effects remain.

2 4 23

Prof Claire Hills

@chillslincoln79.bsky.social

almost 2 years ago

Hello to everyone [email protected] 👋.Follow along for all things #kidney #diabetes & #cardiovascular 👩‍🔬🧪🥼....oh & a bit of wine, interiors & all things a little bit boujee 🥂🕯🏡. The other half of team @UoLRenal with @paulsquires.bsky.social #cardiosky #NephSky #Diabetes #cardiorenal #cardiovascular

2 5 23

Prof Claire Hills

@chillslincoln79.bsky.social

almost 2 years ago

'Effects of sodium–glucose cotransporter 2 inhibitors on cardiovascular and renal outcomes in people with diabetes and advanced chronic kidney disease' 👇👇👇 tinyurl.com/ysd4pr7m #cardiovascular #cardiovasculardisease #SGLT2i #cardiosky #NephSky

tinyurl.com

Effects of sodium–glucose cotransporter 2 inhibitors on cardiovascular and renal outcomes in people with diabetes and advanced chronic kidney disease - Diabetologia

Aims/hypothesis Although the benefits of sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in chronic kidney disease (CKD) are well established, the effects of these therapeutic agents in patients...

1 8 23

Prof Paul E Squires

@paulsquires.bsky.social

almost 2 years ago

Glucagon-like Peptide-1 Receptor Agonists: New Evidence of Kidney and Cardiovascular Protection From the FLOW and SELECT Trials 👇👇👨‍🔬🧪🥼 #cardiacsky #nephsky #medsky #cardiovascular #kidneydisease #Type2diabetes #semaglutide www.ajkd.org/article/S027...

www.ajkd.org

DEFINE_ME

1 6 23

Dame Sa

@damesa.bsky.social

almost 2 years ago

SARS1 survivors suffered from chronic illness and damage to various organs, including the heart. So any doctor surprised by SARS2 doing the same needs to go back to medical school, or get out of medicine. #LongSARS #LongCovid #HeartHealth #Cardiovascular www.thelancet.com/journal….

www.thelancet.com

Multiomic characterisation of the long-term sequelae of SARS survivors: a clinical observational study

Although health outcomes continued to improve, our study suggested that SARS survivors still suffered from physical fatigue, osteoporosis, and necrosis of the femoral head 18 years after discharge, po...

0 10 23

Tamim Ahsan

@tamim-ahsan.bsky.social

about 1 year ago

New Research Finds Long-Term Shifts in Heart Disease Mortality #heartdisease #cardiovascular #mortality #death #healthcare 🧪 jamanetwork.com/journals/….

jamanetwork.com

Heart Disease Deaths Have Changed

This Medical News article discusses a decades-long decline in heart disease deaths and an evolution from ischemic heart disease mortality to other cardiovascular causes, such as heart failure, cardiac...

1 6 22