#RNATherapeutics

www.nature.com

Chemical and topological design of multicapped mRNA and capped circular RNA to augment translation - Nature Biotechnology

mRNA cap designs boost translation >10-fold, with potential benefits for RNA therapies.

buff.ly

mRNA initiation and termination are spatially coordinated - PubMed

Transcriptional initiation and termination decisions drive messenger RNA (mRNA) isoform diversity but the relationship between them remains poorly understood. By systematically profiling joint usage of...

www.linkedin.com

#invernatherapeutics #mjff #grant #parkinsonsdisease #lrrk2 #biotech #startup #neuroscience #innovation | Inverna Therapeutics

🎉 Exciting news from Inverna Therapeutics! 🚀 We’re honored to announce that Inverna has been awarded a grant from the Michael J. Fox Foundation for Parkinson’s Research (MJFF) as part of the LRRK2 Inv...

buff.ly

TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD - PubMed

Motor neuron hyperexcitability is a broadly observed yet poorly understood feature of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Nuclear depletion and cytoplasmic aggregation...

time.com

TIME100 Health: Victor Ambros and Gary Ruvkun

Find out why they're on the TIME100 Health list.

doi.org

TAV2b Peptide Derivatives Underwind and Stabilize Double-Stranded RNA upon Binding

Double-stranded RNA (dsRNA) has become an essential tool to understand biological processes with promising therapeutic implications. However, its usage is often limited due to poor cellular uptake and...

dlvr.it

Molecular Therapy Presents: AI-Powered Precision Medicine: From…

Join industry experts for a free deep dive into how artificial intelligence is transforming precision medicine. Learn how AI tools are optimizing drug…