#RNAsky is an active hashtag on Bluesky. In the last 30 days, 9 people shared 20 posts with it — around 1 a day. Activity is down 33% versus the previous week, peaking on Jul 18 with 2 posts.
thawanilab.org
The Thawani Lab at Columbia University
The Thawani Lab at Columbia University describing their research on mobile genome, cryo-electron microscopy and genome engineering
RNA biology
Starter pack by Dr Zeinab Rekad 🔬🧬🧪
A non exhaustive list of cool RNA researchers and labs.
www.pnas.org
Improved RNA stability estimation through Bayesian modeling reveals most Salmonella transcripts have subminute half-lives | PNAS
RNA decay is a crucial mechanism for regulating gene expression in response to environmental stresses. In bacteria, RNA-binding proteins (RBPs) are...
rdcu.be
Ribosomes hibernate on mitochondria during cellular stress
Nature Communications - Cells adapt to low glucose by halting protein synthesis and altering organelle shape. Here the authors showed that hibernating ribosomes tether to mitochondria and form...
sinha.biochem.utah.edu
The Sinha Lab
The Sinha lab studies key aspects of protein synthesis and translational control in healthy and diseased states. We study the multifaceted roles of ribosomes as critical sensors of cellular stress.
www.nature.com
Intracellular pathogen effector reprograms host gene expression by inhibiting mRNA decay - Nature Communications
Intracellular pathogens hijack host gene expression to subvert cellular processes. Here, the authors show that Legionella pneumophila’s PieF effector inhibits the human CCR4-NOT deadenylation machiner...
go.nature.com
RNA function follows form – why is it so hard to predict?
AlphaFold’s highly accurate structural models transformed protein biology,but RNA lags behind.
academic.oup.com
Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells
Abstract. Although antibody derivatives, such as Fabs and scFvs, have revolutionized the cellular imaging, quantification and tracking of proteins, analogo
Molecular Cell @cp-molcell.bsky.social
Longitudinal monitoring of cytoplasmic RBP-RNA interactions and transcriptome in living cells by engineered protein nanocages
dlvr.it
Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social
Riboseek is a fast RNA/DNA search. More sensitive than nhmmer at 250x speed. Structure-aware realignment produces MSAs approaching rMSA quality. Plus 1.7M precomputed RNA MSAs, and an API to search your own 📄 www.biorxiv.org/content/10.6... 💾 github.com/steineggerla... 🌐 search.foldseek.com/riboseek
www.nature.com
Structural alignments to design functional RNAs - Nature Computational Science
A new method designs RNA sequences by learning from alignments of structurally similar molecules, producing aptamers and ribozymes that are experimentally validated.
www.nature.com
Structure-alignment-driven cross-graph modeling for functional RNA design - Nature Computational Science
This study presents AlignIF, which uses multiple structure alignments to capture evolutionary rules and conservation patterns across RNA families, enabling diverse, structure-guided designs of functio...
Zeynep Baharoglu @zeynepbaharoglu.bsky.social
journals.asm.org/doi/10.1128/... comprehensive review of bacterial RNA modifications 🦠
journals.asm.org
rnastuff.com
A tRNA as an Architectural Scaffold in the Trypanosome Editosome
A transfer RNA (tRNA) was originally seen as a boring adaptor that brings amino acids to the ribosome during protein translation. A tRNA, with its distinct 2D cloverleaf structure, has an amino aci…
Nature Methods @natmethods.nature.com
Chemical-induced gene signatures (CIGS) is a high-resolution dataset of 319,045,108 gene expression events induced by chemical perturbation. www.nature.com/articles/s41...
www.nature.com
Janusz M. Bujnicki @jmbujnicki.bsky.social
Exciting news for the RNA research community! The Human RNome Project has been launched: a global effort to map all human RNAs and their chemical modifications. Proud to support it and contribute to the article in Genome Biology doi.org/10.1186/s130... #RNA #bioinformatics #RNAstructure #modomics
genomebiology.biomedcentral.com
Nature Biomedical Engineering @natbiomedeng.nature.com
Chemically synthesized, non-capped and non-polyadenylated peptide-coding RNA efficiently induces antigen-specific CD8+ T cells
go.nature.com
GW Gant Luxton @gwgl.bsky.social
The nucleolus is the largest condensate in the nucleus and the site where ribosomes are built. It has no membrane. It assembles by phase separation, components demixing from the nucleoplasm into a droplet. So what decides when it forms? 🧵🪱💧 www.biorxiv.org/content/10.6...
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